2022: Time is Everything: Rhythms and Dynamics of Psychopathology Across the Life Span
The APPA meeting in 2022 will examine the importance of timing in the classification, assessment, etiology, risk factors, manifestations, course and consequences of psychopathology. The speakers and discussants will cover the full range of evidence from our growing understanding of the short-term dynamics and rhythms of biologic systems to broader patterns of both contextual and biologic influences on manifestations of psychopathology across the life span. These principles will be applied to evidence about mental disorders including affective disorders, psychosis, substance abuse and other conditions as well as their underlying domains such as mood, anxiety, sleep, attention, behavior, etc. The concepts and research presented will include neural dynamics, critical periods, environmental and intrinsic drivers of within day, daily, weekly, and seasonal rhythms from basic and human studies, determinants of sex differences across life stages, life course patterns derived from developmental psychopathology and aging research and the role of timing of social and environmental influences on health and mental health. These principles will then be applied to identify how such rhythms and dynamics may be incorporated into our conceptualization, classification, risk estimation and treatment of mental disorders.
Kathleen R Merikangas Ph.D.
Senior Investigator, National Institute of Mental Health
2023: Psychopathology and Complexity
Biological psychiatry research has made very significant progress, but it has become clear that brain abnormalities in psychiatric disorders are complex and multifactorial. This complexity is increasingly standing in the way of further advances and development of new treatments. In addition, recent debates around DSM-5, RDoC, HiTOP, clinical staging, and other approaches to psychopathology indicate that our best hope for meaningful progress is to couple better understanding of psychopathology with biological approaches. With this background, the 2023 meeting will focus on “Psychopathology and Complexity”. The meeting will feature speakers describing the state of the art in complex systems science as well as applications of complexity principles to the study of brain and behavior. There will also be opportunities to discuss how brain biology and psychopathology interact and mold one another in a dynamic way and how complexity can help us understand this process. This meeting is intended to stimulate discussion about what complexity science can teach us about the emergence of abnormal experiences.
Dost Ongur, MD, PhD
William P. and Henry B. Test Professor of Psychiatry, Harvard Medical School
Director, Schizophrenia and Bipolar Disorder Research Program, Mclean Hospital